At Klarity, we specialize in advanced, evidence-based treatments designed tohelp you regain mental clarity, emotional balance, and lasting relief from chronic pain.
One of our most impactful therapies is Ketamine Infusion Therapy—a breakthrough treatment shownto rapidly improve symptoms of depression, anxiety, PTSD, andtreatment-resistant conditions, as well as chronic pain disorders such as fibromyalgia,migraines, CRPS, and neuropathic pain.
Ketamine works differently than traditional medications. By targeting glutamate pathways in the brain, it promotes rapid neuroplasticity—the brain’s ability to form new, healthier connections. This process can lead to fast-acting improvements in mood, reduced emotional distress, and a “reset”of pain signaling pathways, helping to decrease long-term discomfort andimprove overall quality of life.
At Klarity, your care is guided by experienced medical professionals in a safe, comfortable, and highly supportive environment. With locations in Castleton and Greenwood, Indiana,we are dedicated to helping you feel better—often faster than you thought possible—and supporting you every step of the way on your journey to healing.

What is Ketamine Therapy?
Ketamine infusion therapy is an advanced treatment that involves the controlled administration of low-dose ketamine through an IV in a safe, medically supervised setting. While ketamine has been used for decades as ananesthetic, it is now widely recognized for its ability to provide rapid relief from depression, anxiety, PTSD, and chronic pain—especially when othertreatments haven’t worked.
Unlike traditional medications that can take weeks to show results, ketamine often begins working within hours to days. It works by targeting the brain’s glutamate system and NMDA receptors, helping to restore healthy communication between brain cells. This process supports neuroplasticity—the brain’s ability to form new, more positive connections—leading to improvements in mood, emotional resilience, and pain regulation.

How Ketamine Works
Ketamine promotes neuroplasticity, helping the brain and nervous system “relearn” healthier patterns of communication. For mental health, this can lead to improved mood, increased motivation, and clearer thinking. For chronic pain, ketamine helps interrupt the cycle of pain signaling—often referred to as the “pain memory loop”—providing relief even for patients whohave not responded to traditional treatments.
Mental Health Treatment
During each session, you’ll relax in a calm, comfortable environment while your ketamine infusion is administered intravenously. Treatments typically last 40–60 minutes. Most patients begin with a series of six infusions over two to three weeks to achieve optimal results.
Pain Management Treatment
Pain treatment protocols are more individualized and generally involve longer infusion sessions. Treatments typically last 2 to 4 hours, depending on your condition and response. Most protocols include a series of 5 to 10 infusions administered over one to two weeks (excluding weekends) for optimal benefit.
Throughout every session, our experienced clinical team closely monitors your comfort, vital signs, and response totreatment—ensuring a safe, supportive, and personalized experience.

Benefits of Ketamine

Decreased Anxiety
Decreased anxiety and irritability

Balanced Mood
Balanced mood and improved resilience

Cognitive Clarity
Greater emotional stability and cognitive clarity

Enhanced Focus
Enhanced mental focus and confidence

Improved Energy
Improved energy and focus and sleep

Increase Motivation
Increased energy and motivation and stamina

Pain Relief
Reduces chronic pain and improves mobility

Sleep Improvement
Improves sleep quality and recovery

Stress Reduction
Supports nervous system balance

Ketamine infusion therapy has shown remarkable effectiveness for individuals struggling with mood disorders—especially those who have not found relief with traditional medications or therapy alone.
Conditions Treated:
- Major Depressive Disorder (MDD)
- Treatment-Resistant Depression
- Anxiety and Panic Disorders
- Post-Traumatic Stress Disorder (PTSD)
- Suicidal Ideation
- Bipolar Depression (non-manic phase)
- OCD and intrusive thought patterns
Mental Health Benefits:
- Rapid reduction in depressive and suicidal thoughts
- Improved mood and motivation
- Enhanced cognitive clarity and focus
- Better emotional regulation and resilience
- Long-term improvement through neuroplasticity
Many patients notice relief within 24–48 hours of their first or second infusion.
Ketamine offers a unique and highly effective approach to treating chronic pain—especially for individuals who have not found relief with traditional therapies. By targeting NMDA receptors in the nervous system, ketamine helps interrupt pain signaling pathways and reduce central sensitization, a process in which the body becomes overly sensitive to pain.
Conditions We Treat:
- Fibromyalgia
- Complex Regional Pain Syndrome (CRPS)
- Chronic migraines
- Neuropathic pain
- Chronic back pain and nerve pain
- Persistent pain following injury or surgery
What Patients Often Experience:
- Reduced pain intensity and sensitivity
- Improved mobility and ability to perform daily activities
- Decreased reliance on opioids or other pain medications
- Relief that may last weeks to months following a treatment series
For many patients, ketamine provides an opportunity to regain function, restore independence, and live with significantly less pain.

What to Expect During Treatment
01
Personalized Consultation
Your journey begins with a comprehensive consultation with one of our experienced providers. We’ll review your medical history, symptoms, and goals to determine if ketamine therapy is right for you and create a personalized treatment plan.
02
Preparation & Comfort
On the day of your treatment, you’ll be welcomed into a calm, private treatment room designed for relaxation. Our team will guide you through what to expect, answer any questions, and ensure you feel comfortable before starting your infusion.
03
Ketamine Infusion Session
Your infusion is administered intravenously while you relax in a comfortable, monitored setting. Most patients experience a deeply calming, introspective state. Our clinical team closely monitors your vital signs and comfort throughout the session to ensure a safe and supportive experience.
04
Recovery & Ongoing Support
After your session, you’ll have time to rest as the effects wear off. Our team will check in with you before discharge and provide guidance for the rest of your day. We’ll also track your progress over time and adjust your treatment plan as needed to help you achieve the best possible results.
Book Your Ketamine Consultation in Indiana
If you’re struggling with depression, anxiety, or chronic pain, you don’t have to keep searching for answers. Ketamine Infusion Therapy may offer the relief you’ve been looking for—especially if other treatments haven’t worked.
At Klarity, we take a personalized, compassionate approach to care—helping you restore balance, build resilience, and feel like yourself again.
Take the first step today.
Schedule your consultation at our Castleton or Greenwood locations and find out if ketamine therapy is right for you.

Locations
Greenwood
Castleton
Frequently Asked Questions
At Klarity, we’re committed to helping you take control of your mental health with compassionate, expert care. Our psychiatric medication management services are designed to provide:
Yes. Many patients experience improvement in both mood and pain levels, as ketamine works on overlapping neural pathways related to emotion and pain perception.
Some patients feel better within 24 hours of their first or second infusion. Pain relief may take a few sessions to build.
Improvements can last weeks to months. Maintenance infusions can extend the benefits over time.
Yes. Ketamine has been used safely in medicine for decades. At Klarity, all infusions are performed under medical supervision in a controlled environment.
Absolutely. Klarity’s providers are experienced in both psychiatric and chronic pain applications of ketamine and can tailor your care to address both conditions if needed.
The cost of ketamine therapy varies depending on your personalized treatment plan and the number of infusions recommended. Klarity offers flexible payment options and will review details during your consultation.
We believe financial considerations should never stand in the way of your healing — our team is here to guide you through every step of the process.
Why Choose Klarity?
Klarity is a trusted provider of advanced mental health and pain management therapies. Led by Dr. Melissa Reed, MD, our team of medical professionals delivers care that is both scientifically grounded and personally compassionate.
We specialize in customized protocols that may include ketamine infusions, Spravato, TMS, hormone optimization, and IV nutrient therapy, helping patients achieve balanced wellness from every angle.
Our Commitment:
- Safe, monitored environment for every infusion
- Personalized dosing tailored to your diagnosis and response
- Options for mental health, chronic pain, or combined protocols
- Two convenient Indiana locations: Castleton and Greenwood
Your comfort and well-being are at the heart of everything we do.

Related Treatments
At Klarity, we offer a range of complementary treatments designed to support both mental and physical wellness, enhance the benefits of ketamine therapy, and promote long-term healing.
Most insurances accepted




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