At Klarity, we specialize in evidence-based treatments that help patients reclaim mental clarity, emotional stability, and physical comfort. One of our most transformative therapies is Ketamine Infusion Therapy — a breakthrough treatment proven to relieve symptoms of depression, anxiety, PTSD, and chronic pain conditions such as fibromyalgia, migraines, CRPS, and neuropathic pain.
Ketamine works by activating glutamate pathways in the brain, promoting rapid neuroplasticity — the brain’s ability to form new, healthier connections. This not only improves mood and emotional regulation but can also reset pain perception pathways, reducing long-term discomfort and restoring quality of life.
With locations in Castleton and Greenwood, Indiana, Klarity Wellness Clinic provides a calm, supportive environment where you can begin your journey toward both emotional and physical healing.
What is Ketamine Therapy?
Ketamine infusion therapy involves the controlled administration of low-dose ketamine through an IV under medical supervision. Originally used safely as an anesthetic for decades, ketamine has gained recognition for its ability to rapidly relieve depression, anxiety, PTSD, and chronic pain.
Unlike traditional medications that may take weeks to work, ketamine acts within hours by modulating glutamate and NMDA receptor activity, enhancing communication between neurons and restoring healthy brain and nervous system function.
How Ketamine Works
Ketamine stimulates neuroplasticity, helping the brain and nervous system “relearn” healthy signaling patterns. For mental health, this means improved mood, motivation, and cognitive function. For pain, it helps disrupt the pain memory loop, offering relief even for those who haven’t responded to traditional pain management therapies.
During each session for mental health, you’ll relax in a comfortable setting while the infusion is administered intravenously. Sessions typically last 40–60 minutes, with most treatment plans including a series of six infusions over two to three weeks for best results.
During each session for pain management, you’ll relax in a comfortable, private setting while the infusion is administered intravenously. Pain protocols differ from mental health treatments and are generally longer and more intensive. Infusions typically last 2 to 4 hours, depending on your condition and individualized dosing plan. Most pain treatment protocols include a series of 5 to 10 infusions administered over the course of one to two weeks (excluding weekends) for optimal results. Throughout each session, our clinical team will carefully monitor your comfort, vitals, and response to treatment to ensure safety and effectiveness.
Benefits of Ketamine
Decreased Anxiety
Decreased anxiety and irritability
Cognitive clarity
Greater emotional stability and cognitive clarity
Increase Motivation
Increased energy, motivation, and stamina
Ketamine infusions are highly effective for individuals with mood disorders who have not found relief through conventional treatments.
Conditions Treated:
- Major Depressive Disorder (MDD)
- Treatment-Resistant Depression
- Anxiety and Panic Disorders
- Post-Traumatic Stress Disorder (PTSD)
- Suicidal Ideation
- Bipolar Depression (non-manic phase)
- OCD and intrusive thought patterns
Mental Health Benefits:
- Rapid reduction in depressive and suicidal thoughts
- Improved mood and motivation
- Enhanced cognitive clarity and focus
- Better emotional regulation and resilience
- Long-term improvement through neuroplasticity
Many patients notice relief within 24–48 hours of their first or second infusion.
Ketamine’s unique mechanism also makes it a powerful treatment for chronic pain syndromes. By acting as an NMDA receptor antagonist, ketamine interrupts pain signaling pathways and reduces central sensitization — a condition in which the nervous system becomes overly reactive to pain.
Conditions Treated:
- Fibromyalgia
- Complex Regional Pain Syndrome (CRPS)
- Chronic Migraines
- Neuropathic Pain
- Chronic Back Pain or Nerve Pain
- Pain after injury or surgery
Pain Management Benefits:
- Reduced pain intensity and sensitivity
- Improved mobility and daily function
- Diminished reliance on opioids or other medications
- Relief that can last weeks to months after treatment series
For many patients, ketamine offers a chance to live more freely, with less pain and greater vitality.
What to Expect During Treatment
Book Your Ketamine Consultation in Indiana
If you’re struggling with depression, anxiety, or chronic pain, Ketamine Infusion Therapy may be the life-changing solution you’ve been searching for.
At Klarity, we provide personalized care to help you rediscover balance, resilience, and relief — both mentally and physically.
Contact us today to schedule your consultation at our Castleton or Greenwood, Indiana locations, and learn how ketamine can help you live with clarity and comfort.
Locations
Greenwood
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Castleton
Frequently Asked Questions
At Klarity, we’re committed to helping you take control of your mental health with compassionate, expert care. Our psychiatric medication management services are designed to provide:
Yes. Many patients experience improvement in both mood and pain levels, as ketamine works on overlapping neural pathways related to emotion and pain perception.
Some patients feel better within 24 hours of their first or second infusion. Pain relief may take a few sessions to build.
Improvements can last weeks to months. Maintenance infusions can extend the benefits over time.
Yes. Ketamine has been used safely in medicine for decades. At Klarity, all infusions are performed under medical supervision in a controlled environment.
Absolutely. Klarity’s providers are experienced in both psychiatric and chronic pain applications of ketamine and can tailor your care to address both conditions if needed.
The cost of ketamine therapy varies depending on your personalized treatment plan and the number of infusions recommended. Klarity offers flexible payment options and will review details during your consultation.
We believe financial considerations should never stand in the way of your healing — our team is here to guide you through every step of the process.
Why Choose Klarity?
Klarity is a trusted provider of advanced mental health and pain management therapies. Led by Dr. Melissa Reed, MD, our team of medical professionals delivers care that is both scientifically grounded and personally compassionate.
We specialize in customized protocols that may include ketamine infusions, Spravato, TMS, hormone optimization, and IV nutrient therapy, helping patients achieve balanced wellness from every angle.
Our Commitment:
- Safe, monitored environment for every infusion
- Personalized dosing tailored to your diagnosis and response
- Options for mental health, chronic pain, or combined protocols
- Two convenient Indiana locations: Castleton and Greenwood
Your comfort and well-being are at the heart of everything we do.
Related Treatments
At Klarity, we offer a range of complementary treatments designed to support both mental and physical wellness, enhance the benefits of ketamine therapy, and promote long-term healing.
Most insurances accepted
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