At Klarity, we understand how discouraging it can feel when depression doesn’t improve with traditional medications or therapy alone. You’re not alone—and there are advanced treatment options available.
We offer Spravato® (esketamine), an FDA-approved, in-office treatment for adults with treatment-resistant depression (TRD) and major depressive disorder (MDD) with suicidal thoughts. Unlike traditional antidepressants, Spravato works by targeting NMDA receptors in the brain—helping to restore balance, improve mood, and deliver relief more rapidly.
Administered under medical supervision in a safe and supportive setting, Spravato provides a new path forward for patients who have not found success with standard treatments. Spravato is available only through the FDA-required SPRAVATO® REMS (Risk Evaluation and Mitigation Strategy) Program, which includes in-office administration and post-treatment monitoring to help ensure patient safety.
With convenient locations in Castleton and Greenwood, Indiana, Klarity is proud to offer innovative, evidence-based care designed to help you feel better and regain a sense of control in your life.
What is Spravato®?
Spravato® (esketamine) is a FDA approved prescription nasal spray derived from ketamine that works differently from traditional antidepressants. Rather than targeting serotonin or dopamine, it acts on the brain’s glutamate system—a key pathway involved in mood, learning, and emotional regulation.
By enhancing communication between brain cells and promoting neuroplasticity, Spravato helps the brain form new, healthier connections. This process can lead to meaningful improvements in mood, clarity, and thought patterns—often more rapidly than standard medications.
Treatment is administered in-office under medical supervision, where patients are monitored throughout each session to ensure a safe and supportive experience.
Spravato offers a new approach for individuals who haven’t found relief with traditional treatments—helping improve symptoms and restore a sense of stability and hope.
- Rapid relief from depressive symptoms and suicidal ideation
- Effective for patients who haven’t responded to traditional antidepressants
- Improves mood, focus, and emotional stability
- Reduces feelings of hopelessness and fatigue
- Safe, FDA-approved, and administered under medical supervision
- Non-invasive with minimal downtime
- Can be used alongside oral antidepressants for enhanced results
Spravato provides a new path forward — one that targets the root of depression to promote lasting healing and resilience.
You may be a good candidate for Spravato if you:
- Have been diagnosed with major depressive disorder (MDD)
- Have not found relief after trying two or more antidepressant medications
- Are experiencing treatment-resistant depression (TRD)
- Struggle with persistent depressive symptoms, including hopelessness or suicidal thoughts
- Are looking for a fast-acting, non-invasive treatment option
- Prefer a structured, in-office therapy with medical supervision
Spravato is designed for adults seeking meaningful improvement in mood, energy, and overall well-being—especially when traditional treatments have not been effective.
What to Expect During Spravato® Treatment
01
Comprehensive Consultation
Your journey begins with a detailed consultation with one of our experienced providers. We’ll review your symptoms, treatment history, and goals to determine if Spravato is the right option and develop a personalized care plan.
02
In-Office Treatment Session
During your appointment, you’ll self-administer Spravato nasal spray under the guidance of our trained medical team. You’ll be seated comfortably in a private treatment room designed to help you feel relaxed and supported throughout the experience.
03
Monitoring & Recovery
After administration, you’ll remain in the clinic for approximately two hours while our team monitors your vital signs, response to treatment, and overall comfort. This ensures your safety and allows time for the medication’s effects to gradually stabilize before you leave.
04
Ongoing Care & Progress Tracking
Spravato is given as part of a structured treatment plan, typically starting with more frequent sessions and gradually decreasing over time. Our team will track your progress closely, adjust your plan as needed, and support you throughout your journey to ensure the best possible outcomes.
Book Your Spravato® Consultation in Indiana
If you’ve tried antidepressants without success, you’re not alone—and there are new options available. Spravato® may offer the breakthrough you’ve been looking for, especially when traditional treatments haven’t provided enough relief.
At Klarity, we specialize in personalized, evidence-based care designed to help you regain stability, clarity, and a renewed sense of hope.
Take the first step today.
Schedule your Spravato consultation at our Castleton or Greenwood locations and find out if this treatment is right for you.
Locations
Greenwood
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Castleton
Why Choose Klarity Wellness Clinic?
Klarity is a trusted provider of advanced, evidence-based mental health treatments in Indiana. Led by Dr. Melissa Reed, MD, our multidisciplinary team delivers care that is both innovative and deeply compassionate.
We specialize in treatment-resistant mood disorders, offering personalized programs that may include Spravato, ketamine infusions, Exomind TMS, and hormone optimization to help you achieve full-spectrum wellness.
Our goal is to help you regain hope, restore mental balance, and reclaim your quality of life — all in a calm, supportive setting.
Most insurances accepted
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